IRAP is a targeted method of reducing inflammation in a joint using your own blood product. At ORCA, we are using this injection for conservative management of chronic knee pain and osteoarthritis. Results have shown to reduce inflammation and pain in patients for six to twelve months.
IRAP (Interleukin-1 Receptor Antagonist Protein) is an anti-inflammatory protein such as Interleukin-1 (IL-1) within the inflamed joint.
IRAP is a product derived from your own blood. A small amount of your blood (60cc per injection) is drawn into a syringe. This is about the same or less than when you donate blood to the blood bank. A centrifuge is then used to separate the blood into 3 parts; plasma, platelet rich plasma, and red blood cells. The plasma is drawn off usually 15-30cc of volume and the red blood cells and platelets are combined and removed normally 7-10cc of volume. The second part of the process involves the use of specialized centrifuge device that uses a small glass bead to further isolate the IRAP to a higher concentration, normally 5-7cc of volume. This is then injected directly into the joint space using a 26 gauge needle.